Discover Serenibiome®: A breakthrough ingredient for a balanced skin microbiome
Serenibiome® is a double patented active ingredient based on flocculosin. This innovative glycolipid is obtained by biofermentation of Pseudozyma flocculosa and was bioinspired by this epiphytic fungus and the holobiont concept. Serenibiome® showcases unprecedented activity, promoting a healthy microbiome and bringing comfort to atopic-prone skin.
Balances Skin Microbiome
Serenibiome® selectively inhibits the growth of Staphylococcus aureus, the opportunistic pathogen prevalent on atopic skin condition, over Staphylococcus epidermidis. By targeting S. aureus, which is implicated in neurogenic inflammatory skin disorders, SERENIBIOME® helps reduce microbiome dysbiosis occuring in the itch-scratch cycle.
Calms skin sensitivity
Serenibiome® calms neurogenic inflammation by reducing the release of IL-8 pro-inflammatory cytokines, induced by Staphylococcus aureus keratinocytes’ stimulation, and ROS production involved in nociception. Furthermore, SERENIBIOME® soothes the itch sensation by increasing the production of well-being neuromediators, well-known to help in pain management by increasing nociceptive threshold, contributing to overall skin comfort and well-being.
Repairs skin barrier
Serenibiome® helps skin repair in compromised skin by boosting the CB2 receptor expression in keratinocytes, known to be at the crossroads of nociception, inflammation, and barrier regeneration. Though it accelerates the re-epithelialization process, enhancing keratinocytes’ migration, inducing barrier regeneration and skin repair.
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